Malignant Neoplasm of the Brain
Profile
- 19-year-old male
- Presents with speech and gait issues
- Neurological condition or malignant neoplasm of the brain?
Work Up
- Lesions in brain stem per MRI contraindicates biopsy
- Suspect glial neoplasm: high grade glioma or H3-3A diffuse midline glioma?
- Summit molecular profile in CSF
Summit™ Report
- Summit test detects H3-3A K28M variant in CSF
- Informs therapeutic intervention: HCP prescribes craniospinal irradiation and temozolomide
