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Case #2 | Obviate Biopsy
Malignant Neoplasm of the Brain
Profile
19-year-old male
Presents with speech and gait issues
Neurological condition or malignant neoplasm of the brain?
Work Up
Lesions in brain stem per MRI contraindicates biopsy
Suspect glial neoplasm: high grade glioma or H3-3A diffuse midline glioma?
Summit molecular profile in CSF
Summit™ Report
Summit test detects H3-3A K28M variant in CSF
Informs therapeutic intervention: HCP prescribes craniospinal irradiation and temozolomide